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DeCS
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Descriptor English:
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Leukocyte Rolling
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Descriptor Spanish:
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Rodamiento de Leucocito
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Descriptor Portuguese:
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Migração e Rolagem de Leucócitos
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Synonyms English:
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Leucocyte Rolling
Rolling, Leucocyte
Rolling, Leukocyte
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Tree Number:
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G04.198.424.233.500
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Definition English:
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Movement of tethered, spherical LEUKOCYTES along the endothelial surface of the microvasculature. The tethering and rolling involves interaction with SELECTINS and other adhesion molecules in both the ENDOTHELIUM and leukocyte. The rolling leukocyte then becomes activated by CHEMOKINES, flattens out, and firmly adheres to the endothelial surface in preparation for transmigration through the interendothelial cell junction. (From Abbas, Cellular and Molecular Immunology, 3rd ed) |
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History Note English:
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2003
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Allowable Qualifiers English:
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Record Number:
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37639
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Unique Identifier:
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D036904
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Occurrence in VHL:
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Similar:
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DeCS
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